The use of Viagra for the first time raised a lot of questions in mind like how it will be beneficial in disease. What is the average dose a healthy person should take? Will the high dosage affect the other organs of our body? How long does it work? What are the major side effects of Viagra? What are the after-effects that are healthy for a human being? Will the use of Viagra cause major health issues in the future? And many more but here we will discuss the answer to some major questions related to Viagra in Erectile dysfunction.
What is viagra?
Viagra helps men with erectile dysfunction during the response to sexual stimulation. It works by filling the penis with enough blood to cause an erection when men are sexually excited.
Viagra is sildenafil citrate a selective citrate salt to inhibit the cGMP (cyclic guanosine monophosphate) specific phosphodiesterase type-5(PDE5) Which helps in the treatment of erectile dysfunction (ED).it will not help in increasing the sexual desire but it relaxes muscles to increase the blood flow that was hampered due to erectile dysfunction (ED). It is a U.S Food and Drug Administration-approved drug to treat erection.
Viagra is rapidly absorbed by blood plasma protein within an hour of oral dosing on empty stomach. The rate of absorption is affected or reduced by taking a high-fat meal. after oral or intravenous dosage, the Viagra salts will excrete as metabolites in feces.
How does Viagra work?
Viagra is the first oral therapy for erectile dysfunction and it involves the release of nitric oxide in the Corpus cavernosum by inhibiting the phosphodiesterase type 5(PDE5) during sexual stimulation that will degrade the guanylate cyclase enzyme to increase the cGMP (cyclic guanosine monophosphate which helps in smooth muscles in corpus cavernosum and increase the inflow of blood to work properly. It works as a vasodilator to increase the blood flow where it is needed the most or to cure erectile dysfunction.
Viagra should be taken before 30-60 minutes before sex and also make sure that your stomach is empty at the time of taking this medicine. It will not prove more beneficial if a person is sick, drunk, or intoxicated than on a healthy person.
It has been proven if Viagra has taken over a high-fat meal the response may be delayed for hours. If the effective hours of Viagra are more than four hours the medical consultation is required.
In the study, it was found that PDE5 concentration is likely lower in platelets, visceral smooth muscles, and skeletal muscles and their inhibition of PDE5 by Viagra may be the basis for the platelet antiaggregatory activity of nitric oxide, peripheral arterial-venous dilation, and formation of a platelet thrombus.
How long does Viagra last?
The long-lasting behavior of these drugs depends upon various factors like the age of patients, dosage, and of course the health of a person. The average dose is 25-100mg is sufficient for up to hours if it has taken 30-60 minutes before sexual activity.
If you are in a healthy state or do not have any health issues and are sexually aroused then it could take effect sooner but underlying conditions much affect the duration of Viagra to work properly in your body and may last longer than an hour.
Depending upon the metabolism of patients, when it is completely absorbed in the bloodstream it will typically last for up to 4 to 5 hours but not in the case of diabetic patients or case of any disease like heart disease or neurological disorder. Medical advice is mandatory if you feel any pain or long erection.
When Viagra is needed?
Before taking any medicine or Viagra one should know the underlying cause of impotence. A consultation from your health provider is needed before you take viagra to maintain your erection. Also, it is important to take caution from you purchasing it and it is also available online.
Some patients will not be comfortable in consultation with the health provider or see a therapist to resolve the psychological issues but if you have trouble in maintaining an erection that’s enough for sex you may take medication like Viagra.
Once you feel that you are not getting the desired results which you want then you should talk to your health provider.
Other than erectile dysfunction, Viagra is also useful in the treatment of pulmonary arterial hypertension (PAH) and high blood pressure.
What are the side effects of Viagra?
Of course, every medicine that has good effects has bad effects too for some specific reason. Here’s below a list of some familiar side effects of Viagra that one can experience mostly.
- Headache only in 16% and common in most of the patients
- Flushing in 10% of patients who have any heart-related problem
- Dyspepsia in 7% of patients who follow an unhealthy diet
- Nasal congestion in 3% of patients who has weak immunity
- Urinary tract infection in 2% of patients
- Abnormal vision in 1% of patients who have prior disorders
- Diarrhea in 2% of patients who drink at an excessive level
- Dizziness in 1% of patients
- Rash in 1% of patients
- Back pain in 1% of patients
- Indigestion in 1% patients
Rarely has it caused heart failure in patients having heart diseases. Prior health problems like diabetes, neurological disorder, and any other health issues increase the risks for experiencing these side-effects listed above.
If you are taking any kind of nitrates-containing medicine regularly then you should not take Viagra anymore because it will cause a drop in blood pressure to an unsafe level.
Viagra is proven to be an effective strategy to treat erectile dysfunction by U.S FDA but take it only if your doctor prescribed it to you after doing a certain physical test. Viagra drug is used to treat ED but is not able for complete cure. If you take Viagra with any nitrates-containing drugs will lead you to a life-threatening level.